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Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
Low-dose or microdosed Accutane is an off-label use of isotretinoin, or Accutane, by which patients take a lower dose of the medication over a longer period of time. But does it make enough of a ...
Accutane causes the skin on the lips to shed so quickly that it can cause thick, chunky flakes to come off, which can worsen and become red if you pick the skin off, says Goldman. He recommends ...
Isotretinoin is a pharmaceutical derivative of retinoic acid (a metabolite of vitamin A). Its mechanism of action is believed to involve reduction in the amount of sebum produced by sebaceous glands on the skin's surface.
The name isotretinoin is the same root tretinoin plus the prefix iso-. Regarding pronunciation, the following variants apply equally to both tretinoin and isotretinoin. Given that retinoic is pronounced / ˌ r ɛ t ɪ ˈ n oʊ ɪ k /, [43] [44] [42] [45] it is natural that / ˌ t r ɛ t ɪ ˈ n oʊ ɪ n / is a commonly heard pronunciation.
And if treating your scalp acne from the outside doesn’t prove effective for you, your doctor may prescribe oral medications, says Dr. Gohara, such as oral antibiotics, hormonal therapy (like ...
The development of oral isotretinoin (sold as Accutane and Roaccutane) followed in 1980. [211] After its introduction in the United States, scientists identified isotretinoin as a medication highly likely to cause birth defects if taken during pregnancy.
Isotretinoin carries a high risk of causing severe birth defects if taken during pregnancy [5] (see Teratogenicity of isotretinoin) and the goals of the iPLEDGE REMS (risk evaluation and mitigation strategy) program are to prevent fetal exposure to isotretinoin and to inform prescribers, pharmacists, and patients about isotretinoin's serious ...
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