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Generally speaking, though, PSA levels for men who are: Age 60 or older: should be at or below 4.0 mg/mL; Age 59 or younger: should be at or below 2.5 mg/mL; The average PSA for men in the younger group is <1.0 mg/mL. Why are my PSA levels elevated? Your PSA levels could be elevated for many reasons.
An increase of 2.0 ng/mL over a year predicts a higher likelihood of death due to aggressive prostate cancer. PSA velocity may help predict survivability from prostate cancer. Men with a PSA increase of 0.35 ng/ML or less over a year have a 92 percent survival rate.
There is no specific normal or abnormal level of PSA in the blood. In the past, PSA levels of 4.0 ng/mL and lower were considered normal. However, some individuals with PSA levels below 4.0 ng/mL have prostate cancer and many with higher PSA levels between 4 and 10 ng/mL do not have prostate cancer (1).
For men in their 40s and 50s: A PSA score greater than 2.5 ng/ml is considered abnormal. The median PSA for this age range is 0.6 to 0.7 ng/ml. For men in their 60s: A PSA score greater than 4.0 ng/ml is considered abnormal. The normal range is between 1.0 and 1.5 ng/ml.
The PSA test can detect high levels of PSA that may indicate the presence of prostate cancer. However, many other conditions, such as an enlarged or inflamed prostate, also can increase PSA levels. Therefore, determining what a high PSA score means can be complicated.
There’s no single PSA level that’s considered normal. In the past, experts considered a PSA of below 4 nanograms per milliliter normal, and many labs may still use this as a cutoff when...
Experts consider PSA levels below 4 nanograms per milliliter (ng/mL) to be typical for most people. Anything higher may indicate that you have cancerous cells in your prostate gland....
Diagnostics & Testing / PSA Test. A PSA (prostate-specific antigen) test is a blood test that helps healthcare providers diagnose and manage prostate cancer. High PSA levels don’t mean you have prostate cancer. But you’re at a higher risk. You may need additional testing and observation to make sure.
Men with a PSA level between 4 and 10 (often called the “borderline range”) have about a 1 in 4 chance of having prostate cancer. If the PSA is more than 10, the chance of having prostate cancer is over 50%.
From there, other types of tests can help with the decision on whether you need a biopsy, including: Digital rectal exam (DRE), if not already done. Free PSA test (measures PSA not bound to proteins in blood; <10% Free PSA indicates greater risk of having cancer; 10-20% is borderline)