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  2. Tetrahydrocannabinolic acid - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrocannabinolic_acid

    Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.

  3. Comparison of phytocannabinoids - Wikipedia

    en.wikipedia.org/wiki/Comparison_of_phyto...

    However, cannabis does not naturally contain significant amounts of THC. Instead, tetrahydrocannabinolic acid (THCA) is found naturally in raw and live cannabis and is non-intoxicating. Over time, THCA slowly converts to THC through a process of decarboxylation over the course of roughly a year, but can be sped up with exposure to high ...

  4. Tetrahydrocannabinolic acid synthase - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrocannabinolic...

    THCA synthase is expressed in the glandular trichomes of Cannabis sativa. THCA synthase may contribute to the self-defense of Cannabis plants by producing THCA and hydrogen peroxide, which are both cytotoxic. Because these products are toxic to the plant, THCA synthase is secreted into the trichome storage cavity. [7]

  5. Decarboxylation - Wikipedia

    en.wikipedia.org/wiki/Decarboxylation

    The decarboxylation of this compound by heat is essential for the psychoactive effect of smoked cannabis, and depends on conversion of the enol to a keto group when the alpha carbon is protonated. Upon heating, Δ9-tetrahydrocannabinolic acid decarboxylates to give the psychoactive compound Δ9- Tetrahydrocannabinol . [ 13 ]

  6. Cannabidiolic acid - Wikipedia

    en.wikipedia.org/wiki/Cannabidiolic_acid

    Cannabidiolic acid (CBDA), is a cannabinoid produced in cannabis plants. [1] It is the precursor to cannabidiol (CBD). It is most abundant in the glandular trichomes on the female seedless flowers or more accurately infructescence often colloquially referred to as buds or flowers.

  7. Chemical defenses in Cannabis - Wikipedia

    en.wikipedia.org/wiki/Chemical_defenses_in_Cannabis

    Close up of a Cannabis plant. Cannabis (/ˈkænəbɪs/) is commonly known as marijuana or hemp and has two known strains: Cannabis sativa and Cannabis indica, both of which produce chemicals to deter herbivory. The chemical composition includes specialized terpenes and cannabinoids, mainly tetrahydrocannabinol (THC), and cannabidiol (CBD ...

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  9. Cannabinoid - Wikipedia

    en.wikipedia.org/wiki/Cannabinoid

    Cannabis plants can exhibit wide variation in the quantity and type of cannabinoids they produce. The mixture of cannabinoids produced by a plant is known as the plant's cannabinoid profile. Selective breeding has been used to control the genetics of plants and modify the cannabinoid profile.

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