Search results
Results from the WOW.Com Content Network
When a non-competitive inhibitor is added the Vmax is changed, while the Km remains unchanged. According to the Lineweaver-Burk plot the Vmax is reduced during the addition of a non-competitive inhibitor, which is shown in the plot by a change in both the slope and y-intercept when a non-competitive inhibitor is added. [8]
Non-competitive inhibition does not change K m (i.e., it does not affect substrate binding) but decreases V max (i.e., inhibitor binding hampers catalysis). [24]: 97 Mixed-type inhibitors bind to both E and ES, but their affinities for these two forms of the enzyme are different (K i ≠ K i ').
On the other hand, the V max will decrease relative to an uninhibited enzyme. On a Lineweaver-Burk plot, the presence of a noncompetitive inhibitor is illustrated by a change in the y-intercept, defined as 1/V max. The x-intercept, defined as −1/K M, will remain the same. In competitive inhibition, the inhibitor will bind to an enzyme at the ...
If the inhibitor is different from the substrate, then competitive inhibition will increase Km while Vmax remains the same, and non-competitive will decrease Vmax while Km remains the same. However, under substrate inhibiting effects where two of the same substrate molecules bind to the active sites and inhibitory sites, the reaction rate will ...
In electromagnetic theory, the phase constant, also called phase change constant, parameter or coefficient is the imaginary component of the propagation constant for a plane wave. It represents the change in phase per unit length along the path traveled by the wave at any instant and is equal to the real part of the angular wavenumber of the wave.
Some of the important wave processes are refraction, diffraction, reflection, wave breaking, wave–current interaction, friction, wave growth due to the wind, and wave shoaling. In the absence of the other effects, wave shoaling is the change of wave height that occurs solely due to changes in mean water depth – without alterations in wave ...
Uncompetitive inhibition (which Laidler and Bunting preferred to call anti-competitive inhibition, [1] but this term has not been widely adopted) is a type of inhibition in which the apparent values of the Michaelis–Menten parameters and are decreased in the same proportion.
The velocity factor (VF), [1] also called wave propagation (relative) speed or (relative) velocity of propagation (VoP or ), [2] of a transmission medium is the ratio of the speed at which a wavefront (of an electromagnetic signal, a radio signal, a light pulse in an optical fibre or a change of the electrical voltage on a copper wire) passes through the medium, to the speed of light in vacuum.