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A more refined prognosis can be established by consideration of prostate-specific antigen, and grade (i.e. Gleason score in the Gleason grading system). For example, it is common to classify patients into high, intermediate and low-risk groups on the basis of these three factors (TNM stage, PSA and Gleason score).
For example, if the most prevalent pattern/grade is 2, and the second most prevalent grade is 1, then the Gleason score is 2+1=3. If the neoplasm has only one pattern, the grade of that pattern is doubled to obtain the score. For example, if a tumor is entirely grade 1, the Gleason score would be 1+1=2.
The Beckett price guide is a graded card price guide, which means it is graded by a 1–10 scale, one being the lowest possible score and ten the highest. In addition, Professional Sports Authenticator (PSA) grades cards 1–10, and can authenticate autographs as well. Other grading companies include Beckett, SGC, and CGC.
What Your PSA Test Results Mean. THE PSA IS a good initial “check engine light” for the prostate, says Garrett Pohlman, M.D., a urologist and host of The Prostate Health Podcast. But it can ...
PSA was launched in July 1991 by David Hall, owner of the coin grading company Professional Coin Grading Service (PCGS), to serve collectors as a third-party card grader. [1] At the outset, the business faced difficulties owing to a limited demand from collectors who sought card grading services. [ 2 ]
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
PAP immunohistochemical staining is often used with PSA (staining), by pathologists, to help distinguish poorly differentiated carcinomas.For example, poorly differentiated prostate adenocarcinoma (prostate cancer) and urothelial carcinoma (bladder cancer) may appear similar under the microscope, but PAP and PSA staining can help differentiate them; [7] prostate adenocarcinoma often stains ...
Prostate-specific antigen. Prostate-specific antigen (PSA) is secreted by the epithelial cells of the prostate gland and can be detected in a sample of blood. [14] PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. [15]