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2. Lipoic acid - Wikipedia

   en.wikipedia.org/wiki/Lipoic_acid

   Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.

3. Acceptable daily intake - Wikipedia

   en.wikipedia.org/wiki/Acceptable_Daily_Intake

   Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]

4. Tolerable daily intake - Wikipedia

   en.wikipedia.org/wiki/Tolerable_daily_intake

   Tolerable daily intake (TDI) refers to the daily amount of a chemical contaminant that has been assessed safe for human being exposure on long-term basis (usually whole lifetime). [1] TDI specifically occurs to chemicals that humans are exposed to unintentionally or as a contaminant, [ 1 ] where acceptable daily intake refers to chemicals that ...

5. Effective dose (pharmacology) - Wikipedia

   en.wikipedia.org/wiki/Effective_dose_(pharmacology)

   The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

6. Alpha lipoic acid - Wikipedia

   en.wikipedia.org/?title=Alpha_lipoic_acid&...

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7. Dose (biochemistry) - Wikipedia

   en.wikipedia.org/wiki/Dose_(biochemistry)

   In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. If multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that should be broken up ...