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Taste bud. The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste (flavor). [1] Taste is the perception stimulated when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue.
A taste receptor or tastant is a type of cellular receptor that facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact with saliva and are bound to taste receptors in the oral cavity and other locations. Molecules which give a sensation of taste are considered "sapid". [1]
The primary gustatory cortex (GC) is a brain structure responsible for the perception of taste.It consists of two substructures: the anterior insula on the insular lobe and the frontal operculum on the inferior frontal gyrus of the frontal lobe. [1]
The type II taste bud cells make up about another third of the cells in the taste bud and express G-protein coupled receptors that are associated with chemoreception. They usually express either type 1 or type 2 taste receptors, but one cell might detect different stimuli, such as umami and sweetness. [5]
The gustatory cortex is the primary receptive area for taste. The word taste is used in a technical sense to refer specifically to sensations coming from taste buds on the tongue. The five qualities of taste detected by the tongue include sourness, bitterness, sweetness, saltiness, and the protein taste quality, called umami.
Taste cells synapse with primary sensory axons of three cranial nerves; the facial nerve, glossopharyngeal nerve, and the vagus nerve. These cranial nerves innervate the taste buds in the tongue, palate, epiglottis, and esophagus. The primary sensory neurons of these central axons are in the cranial nerve ganglia of each respective cranial nerve.
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Umami represents the taste of the amino acid L-glutamate and 5'-ribonucleotides such as guanosine monophosphate (GMP) and inosine monophosphate (IMP). [14] It can be described as a pleasant "brothy" or "meaty" taste with a long-lasting, mouthwatering and coating sensation over the tongue.