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  2. Benzophenone imine - Wikipedia

    en.wikipedia.org/wiki/Benzophenone_imine

    Primary amines can be protected as benzophenone imines, and the protected amines are stable in flash chromatography. [7] Buchwald-Hartwig amination involves coupling aromatic halide and amine to form carbon-nitrogen bonds with the help of palladium-based catalysts. Benzophenone imine can be used as an ammonia-equivalent in such reactions. [1]

  3. Imine - Wikipedia

    en.wikipedia.org/wiki/Imine

    The general structure of an imine. ... Rarer than primary amines is the use of ammonia to give a primary imine. ... as illustrated with benzophenone imine: [28] (C 6 ...

  4. Buchwald–Hartwig amination - Wikipedia

    en.wikipedia.org/wiki/Buchwald–Hartwig_amination

    Several strategies have been developed to overcome this based on reagents that serve as ammonia equivalents. The use of a benzophenone imine or silylamide can overcome this limitation, with subsequent hydrolysis furnishing the primary aniline. [37] [38] [39]

  5. C13H11N - Wikipedia

    en.wikipedia.org/wiki/C13H11N

    Benzophenone imine, an organic compound with the formula of (C 6 H 5) 2 C=NH; 2-Aminofluorene, a synthetic arylamine This page was last edited on 28 February 2023, at ...

  6. Benzophenone - Wikipedia

    en.wikipedia.org/wiki/Benzophenone

    Benzophenone is a naturally occurring organic compound with the formula (C 6 H 5) 2 CO, generally abbreviated Ph 2 CO. Benzophenone has been found in some fungi, fruits and plants, including grapes. [4] It is a white solid with a low melting point and rose-like odor [5] that is soluble in organic solvents. Benzophenone is the simplest ...

  7. Benzylamine - Wikipedia

    en.wikipedia.org/wiki/Benzylamine

    Benzylamine is used as a masked source of ammonia, since after N-alkylation, the benzyl group can be removed by hydrogenolysis: [10] C 6 H 5 CH 2 NH 2 + 2 RBr → C 6 H 5 CH 2 NR 2 + 2 HBr C 6 H 5 CH 2 NR 2 + H 2 → C 6 H 5 CH 3 + R 2 NH. Typically a base is employed in the first step to absorb the HBr (or related acid for other kinds of ...

  8. Leuckart reaction - Wikipedia

    en.wikipedia.org/wiki/Leuckart_reaction

    The Leuckart reaction is the chemical reaction that converts aldehydes or ketones to amines.The reaction is an example of reductive amination. [1] The reaction, named after Rudolf Leuckart, uses either ammonium formate or formamide as the nitrogen donor and reducing agent.

  9. Peroxide process - Wikipedia

    en.wikipedia.org/wiki/Peroxide_process

    This mixture does not react with ammonia directly but does so in the presence of methyl ethyl ketone to give the oxaziridine. Balanced equations for the individual steps are as follows. Imine formation through condensation: Me(Et)C=O + NH 3 → Me(Et)C=NH + H 2 O. Oxidation of the imine to the oxaziridine: Me(Et)C=NH + H 2 O 2 → Me(Et)CONH ...

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