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It is used as a cream or ointment applied to the skin. [6] Common side effects include itchiness and rash at the site of application, headache, and nausea. [6] Long term use may result in increased growth of fungi. [6] Use during pregnancy and breastfeeding appears to be safe. [6] Mupirocin is chemically a carboxylic acid. [8]
However, widespread use of mupirocin is associated with development of mupirocin-resistant strains of MRSA, with one hospital in Canada experiencing an increase from 2.7% to 65% resistant strains in three years. [78]
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
Germolene is the brand name used on a range of antiseptic products produced by the Bayer company, [1] who purchased the brand from SmithKline Beecham (later GlaxoSmithKline) in 1999. It is manufactured for Bayer UK by the Devon-based Wrafton Laboratories [2] division of US over-the counter and supermarket own-label preparation producer Perrigo. [3]
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
Betafusin (fusidic acid/betamethasone valerate topical cream in Greece) Betafucin (2% fusidic acid/1% betamethasone valerate topical cream in Egypt)(of Delta Pharma S.A.E., A.R.E. (Egypt)) Fusimax (of Roussette in India) Fusiderm (topical cream and ointment by Indi Pharma in India) Fusid (in Nepal) Fudic (topical cream in India)
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Antibiotics, either as a cream or by mouth, are usually prescribed. Mild cases may be treated with mupirocin ointments. In 95% of cases, a single seven-day antibiotic course results in resolution in children. [20] [21] It has been advocated that topical antiseptics are inferior to topical antibiotics, and therefore should not be used as a ...
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