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Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations. Little is understood about how it starts. Nonfamilial early-onset AD can develop in people who are in their 30s or 40s, but this is extremely rare, [3] and mostly people in their 50s or early 60s are affected.
The American Journal of Alzheimer's Disease & Other Dementias is abstracted and indexed in, among other databases: SCOPUS, and the Social Sciences Citation Index. According to the Journal Citation Reports, its 2010 impact factor is 1.774, ranking it 104 out of 185 journals in the category 'Clinical Neurology'.
Early onset dementia is less common than late onset dementia, the former accounting for approximately 10% of dementias globally. [3] Recent studies estimate the prevalence of early onset dementia to be approximately 3.55 million people aged 30–64 worldwide, and will triple by 2050. [6] with an incidence of 119 per 100,000 individuals. [1]
Cognitive decline can begin years before signs of dementia set in, which for some can be as early as age 30, a condition known as young-onset dementia.Globally, it’s estimated nearly 4 million ...
Young-onset dementia happens before the age of 65, with late-onset dementia occurring after, says Dale Bredesen, M.D., neuroscience researcher and singleton chair in neurology at the Pacific ...
A new expert report, published in the journal Stroke, reviews the latest research and explains that three common cardiovascular diseases in adults — heart failure, atrial fibrillation (AFib ...
Early onset familial Alzheimer's disease can be attributed to mutations in one of three genes: those encoding amyloid-beta precursor protein (APP) and presenilins PSEN1 and PSEN2. [40] Most mutations in the APP and presenilin genes increase the production of a small protein called amyloid beta (Aβ)42, which is the main component of amyloid ...
The onset of dementia can come as a shock, but various signs could predict the condition as long as 20 years before symptoms. A new study published by the RAND Corporation in California identified ...
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