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  2. Cushing's syndrome (veterinary) - Wikipedia

    en.wikipedia.org/wiki/Cushing's_syndrome...

    Disadvantages of mitotane as a treatment include the side effects and the requirement for blood test monitoring. Issues can arise when too much of the adrenal cortex becomes eroded. Approximately 30% of dogs will experience a reaction in response to treatment with mitotane; prednisone may be used as an antidote. In the event of a reaction ...

  3. Lymphocyte-variant hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte-variant_hyper...

    Reslizumab, a newly developed antibody directed against interleukin 5 that has been successfully used to treat 4 patients with the hypereosinophilic syndrome, may also be of use for lymphocyte-variant eosinophilia. [4] [5] [10] [11] Patients suffering minimal or no disease complications have gone untreated. [4]

  4. Hypereosinophilic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hypereosinophilic_syndrome

    Depending on eosinophil target-organ infiltration, the clinical presentation of hypereosinophilic syndrome (HES) varies from patient to patient. [13] Individuals with myeloproliferative variant HES may be more likely to experience mucosal ulcerations involving the genitalia or airways, while patients with lymphocytic variant HES typically exhibit prominent skin symptoms such as urticarial ...

  5. Eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia

    The idiopathic hypereosinophilic syndrome is a disorder characterized by hypereosiophilia that is associated with eosinophil-based tissue or organ damage. While almost any organ or tissue may be damaged, the lung, skin, heart, blood vessels, sinuses, kidneys, and brain are the most commonly affected. [ 7 ]

  6. Glaxo Gets FDA Nod for Nucala for Hypereosinophilic Syndrome

    www.aol.com/news/glaxo-gets-fda-nod-nucala...

    Glaxo's (GSK) Nucala becomes the first and only targeted biologic treatment to be approved for hypereosinophilic syndrome (HES), a rare disease caused by eosinophilic inflammation.

  7. List of dog diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_dog_diseases

    Replacement of estrogens, phenylpropanolamine, and surgery have all been used for treatment. [160] Reproductive diseases Prostate disease* in dogs includes benign prostatic hyperplasia (BPH), prostatitis (infection of the prostate), cancer, and cysts and abscesses. BPH is the most common and is found in older intact (not neutered) dogs.

  8. Clonal hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Clonal_hypereosinophilia

    Clonal hypereosinophilia, also termed primary hypereosinophilia or clonal eosinophilia, is a grouping of hematological disorders all of which are characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow, blood, and other tissues.

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