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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
The doctor can look for potential underlying causes, including dementia, medication effects, or environmental factors, Elhelou says. From there, they can suggest effective ways to help you manage ...
Clomipramine. Doxepin. Imipramine. Older antidepressant medications like tricyclic antidepressants typically have a higher risk of side effects than the more modern SSRI and SNRI medications ...
Side effects may also be less troublesome if treatment is initiated with low doses and then gradually increased, although this may also delay the beneficial effects. TCAs can behave like class 1A antiarrhythmics , as such, they can theoretically terminate ventricular fibrillation, decrease cardiac contractility and increase collateral blood ...
Anafranil (clomipramine) – a tricyclic antidepressant; mostly used to treat OCD; Antabuse – inhibits the enzyme acetaldehyde dehydrogenase, causing acetaldehyde poisoning when ethanol is consumed; used to cause severe hangover when drinking; increases liver, kidney, and brain damage from drinking
Indeed there is now emerging evidence that anticholinergic drugs are a risk factor for the induction of Alzheimer's disease when given over the long-term to an elderly population. This drug, therefore, probably should not be used in the elderly at all, especially when there are so many alternatives that do not suffer this serious downside of ...
Falls can be serious — and even deadly — in older adults and the elderly. They’re also common: More than 1 out of 4 older adults falls each year, but less than half of those inform their ...
All-in-all, however, it is prescribed with caution to the elderly and with extreme caution to those with psychosis, as the general brain activity enhancement in combination with the "dementing" effects of anticholinergics increases the potential of imipramine to cause hallucinations, confusion and delirium in this population.
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