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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
Side effects may also be less troublesome if treatment is initiated with low doses and then gradually increased, although this may also delay the beneficial effects. TCAs can behave like class 1A antiarrhythmics , as such, they can theoretically terminate ventricular fibrillation, decrease cardiac contractility and increase collateral blood ...
Anafranil (clomipramine) – a tricyclic antidepressant; mostly used to treat OCD; Antabuse – inhibits the enzyme acetaldehyde dehydrogenase, causing acetaldehyde poisoning when ethanol is consumed; used to cause severe hangover when drinking; increases liver, kidney, and brain damage from drinking
Headaches are one of the most common medical conditions, with 96% of people having at least one in their lifetime, according to Cleveland Clinic. About 40% of people globally experience what are ...
MAOIs also interact with tobacco-containing products (e.g. cigarettes) and may potentiate the effects of certain compounds in tobacco. [34] [35] [36] This may be reflected in the difficulty of smoking cessation, as tobacco contains naturally occurring MAOI compounds in addition to the nicotine. [34] [35] [36]
To lower your risk of developing dementia, the Mayo Clinic suggests taking these steps: Try to keep your mind active. Be physically and socially active. Avoid smoking. Get enough vitamin D.
Most muscle cramps subside within seconds to minutes, although soreness related to the cramps can sometimes last hours to days, per Mayo Clinic. Noted: Building muscle requires a higher protein ...
Effects of chloro, methoxy and trifluoromethyl substituents in the aromatic ring of cycloalkanol ethylamine scaffold were tested. The results showed that the strongest electron-withdrawing m -trifluoromethyl analogue exhibited the most potent inhibitory effect of norepinephrine and the most selectivity over serotonin uptake. [ 36 ]