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2. Indole-3-carbaldehyde - Wikipedia

   en.wikipedia.org/wiki/Indole-3-carbaldehyde

   Lactobacillaceae (Lactobacillus s.l.) species metabolize tryptophan into indole-3-aldehyde (I3A) which acts on the aryl hydrocarbon receptor (AhR) in intestinal immune cells, in turn increasing interleukin-22 (IL-22) production. [2] Indole itself triggers the secretion of glucagon-like peptide-1 (GLP-1) in intestinal L cells and acts as a ...

3. Indole - Wikipedia

   en.wikipedia.org/wiki/Indole

   Indole is an organic compound with the formula C 6 H 4 CCNH 3. Indole is classified as an aromatic heterocycle. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indoles are derivatives of indole where one or more of the hydrogen atoms have been replaced by substituent groups.

4. 6-Formylindolo (3,2-b)carbazole - Wikipedia

   en.wikipedia.org/wiki/6-Formylindolo(3,2-b)carbazole

   In addition to the light- or H 2 O 2-induced formation of FICZ, a number of other enzymatic pathways have been identified to convert Trp to FICZ via the precursor I3A. [2] [3] Oxidative deamination of Trp by aromatic amino acid aminotransferases (ArAT) or L-amino oxidases (LAAO), one of which is the IL4-inducible enzyme IL4I1, converts Trp to indole-3-pyruvate, which after decarboxylation ...

5. Indoleacetate decarboxylase - Wikipedia

   en.wikipedia.org/wiki/Indoleacetate_decarboxylase

   The first one consists of the degradation of the amino acid into indole-3-acetate. And in the second step, IAD catalyzes the decarboxylation of the indole-3-acetate to form the final product, skatole. The decarboxylation of indole-3-acetate is chemically difficult since it leaves an unstable carbanion because of the direct elimination of CO 2.

6. β-Carboline - Wikipedia

   en.wikipedia.org/wiki/Β-Carboline

   β-Carboline (9H-pyrido[3,4-b]indole) represents the basic chemical structure for more than one hundred alkaloids and synthetic compounds. The effects of these substances depend on their respective substituent. Natural β-carbolines primarily influence brain functions but can also exhibit antioxidant [1] effects.

7. Indolepyruvate decarboxylase - Wikipedia

   en.wikipedia.org/wiki/Indolepyruvate_decarboxylase

   The enzyme indolepyruvate decarboxylase (EC 4.1.1.74) catalyzes the chemical reaction. 3-(indol-3-yl)pyruvate 2-(indol-3-yl)acetaldehyde + CO 2. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds.

8. Biological activity - Wikipedia

   en.wikipedia.org/wiki/Biological_activity

   In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. [1] [2] When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. Among the various properties of ...

9. Carbazole - Wikipedia

   en.wikipedia.org/wiki/Carbazole

   The compound's structure is based on the indole structure, but in which a second benzene ring is fused onto the five-membered ring at the 2–3 position of indole (equivalent to the 9a–4a double bond in carbazole, respectively). Carbazole is a constituent of tobacco smoke. [3]