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CR includes a heightened pain sensitivity, and decreased body temperature, and might cause discomfort, thus motivating the drug user to continue usage of the drug. This is one of several ways classical conditioning might be a factor in drug addiction and dependence. [2] In a classic experiment, Shepard Siegel conditioned rats with morphine ...
[4] [3] Responses to a drug cue can be physiological (e.g., sweating, salivation, brain activity), behavioral (e.g., drug seeking), or symbolic expressive (e.g., craving). [3] The clinical utility of cue reactivity is based on the conceptualization that drug cues elicit craving which is a critical factor in the maintenance and relapse to drug use.
Contact high is a phenomenon that occurs in otherwise sober people who experience a drug-like effect just by coming into contact with someone who is under the influence of a psychoactive drug. In a similar way to the placebo effect, a contact high may be caused by classical conditioning as well as by the physical and social setting. [8] [9]
Classical conditioning occurs when a conditioned stimulus (CS) is paired with an unconditioned stimulus (US). Usually, the conditioned stimulus is a neutral stimulus (e.g., the sound of a tuning fork), the unconditioned stimulus is biologically potent (e.g., the taste of food) and the unconditioned response (UR) to the unconditioned stimulus is an unlearned reflex response (e.g., salivation).
The higher the frequency with which a test animal emits the operant behavior, the more rewarding (and addictive), the test substance is considered. Self-administration of addictive drugs has been studied using humans, [1] non-human primates, [2] mice, [3] invertebrates such as ants, and, most commonly, rats.
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
Spontaneous recovery is associated with the learning process called classical conditioning, in which an organism learns to associate a neutral stimulus with a stimulus which produces an unconditioned response. As a result, the previously neutral stimulus comes to produce its own response, which is usually similar to that produced by the ...
Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.