Search results
Results from the WOW.Com Content Network
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
This condition was first discovered in 1995 by Melberg et al. when they described 5 members of a 4-generation Swedish family where cerebellar ataxia and sensorineural deafness presented as an autosomal dominant trait, 4 of them had narcolepsy and 2 had diabetes mellitus. The oldest members had psychiatric symptoms, neurological anomalies, and ...
Narcolepsy with cataplexy is considered an autoimmune-mediated disorder, so some therapies based on this hypothesis have been developed. Immunological therapies developed include: [ 20 ] Corticosteroids : after testing in 1 human and 1 canine case it proved to be ineffective so is less likely to be further used.
Narcolepsy with cataplexy 347.01 G47.411 Narcolepsy without cataplexy 347.00 G47.419 Narcolepsy due to medical condition 347.10 G47.421 Narcolepsy, unspecified 347.00 G47.43 Recurrent hypersomnia 780.54 G47.13 - Kleine-Levin Syndrome: 327.13 G47.13 - Menstrual-related hypersomnia 327.13 G47.13 Idiopathic hypersomnia with long sleep time 327.11 ...
Beginning with the fifth edition, it is intended that diagnostic guideline revisions will be added incrementally. [49] The DSM-5 is identified with Arabic rather than Roman numerals, marking a change in how future updates will be created. Incremental updates will be identified with decimals (DSM-5.1, DSM-5.2, etc.), until a new edition is ...
Pages in category "Narcolepsy" The following 10 pages are in this category, out of 10 total. This list may not reflect recent changes. ...
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
The full mechanism of action of sodium oxybate is poorly understood. [ 3 ] [ 7 ] GHB is a normal metabolite of GABA that interacts with the GABA B receptor and the GHB receptor . [ 3 ] It has been shown to enhance the restorativeness of sleep in part by altering sleep architecture in narcoleptic patients.