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Central serous chorioretinopathy (CSC or CSCR), also known as central serous retinopathy (CSR), is an eye disease that causes visual impairment, often temporary, usually in one eye. [ 1 ] [ 2 ] When the disorder is active it is characterized by leakage of fluid under the retina that has a propensity to accumulate under the central macula.
Optic neuropathy is damage to the optic nerve from any cause. The optic nerve is a bundle of millions of fibers in the retina that sends visual signals to the brain. Damage and death of these nerve cells, or neurons, leads to characteri
Long-term phase: To avoid adverse effects of long-term steroids and to avoid relapse of disease, physicians can transition to a steroid-sparing agent. B-cell depleting therapy , [ 4 ] azathioprine , methotrexate , cyclophosphamide , mycophenolate , IVIG , plasma exchange , cyclosporine , and infliximab have been used.
There are several causes of toxic optic neuropathy. [1] Among these are: ingestion of methanol (wood alcohol), ethylene glycol (automotive antifreeze), disulfiram (used to treat chronic alcoholism), halogenated hydroquinolones (amebicidal medications), ethambutol and isoniazid (tuberculosis treatment), and antibiotics such as linezolid and chloramphenicol as well as chloroquine and the related ...
The photo stress test is clinically useful in diabetes, [3] glaucoma, [3] macular degeneration [4] etc. Diabetic retinopathy affects the microvasculature of the inner retina and causes neurodegeneration. Several studies reported that PSRT is elevated in people with diabetes. [3]
Cherry red spot in a person with central retinal artery occlusion. Central retinal artery occlusion is characterized by painless, acute vision loss in one eye. [1] Upon fundoscopic exam, one would expect to find: cherry-red spot (90%) (a morphologic description in which the normally red background of the choroid is sharply outlined by the swollen opaque retina in the central retina), retinal ...
Long-term use of such medications must be closely monitored, however, due to the discomforting and potentially debilitating and life-threatening side-effects. [ 11 ] [ 12 ] Immunosuppressive drugs such as the therapeutic monoclonal antibody daclizumab , ciclosporin , methotrexate and Adalimumab , sold under the trade name Humira, have proven to ...
The two sides of the RPE include the choroid side, where blood vessels form and bring nourishment to the eye, and the photoreceptor side, with rods and cones that receive light signals.) In particular, the RPE secretes vascular endothelial growth factor (VEGF) at its basement membrane, with the VEGF reaching the choriocapillaris to maintain ...