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Dysautonomia, autonomic failure, or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does not work properly. This condition may affect the functioning of the heart , bladder , intestines , sweat glands , pupils , and blood vessels.
Autonomic neuropathy is one cause of malfunction of the autonomic nervous system (referred to as dysautonomia), but not the only one; some conditions affecting the brain or spinal cord also may cause autonomic dysfunction, such as multiple system atrophy, and therefore, may cause similar symptoms to autonomic neuropathy.
In primary dysautonomias, the autonomic dysfunction occurs as a primary condition (as opposed to resulting from another disease). [1] Autonomic failure is categorized as "primary" when believed to result from a chronic condition characterized by degeneration of the autonomic nervous system, or where autonomic failure is the predominant symptom ...
Cerebellar dysfunction - difficulty coordinating movement and balance [15] Autonomic nervous system dysfunction - impaired automatic body functions, including one, some, or all of the following: [16] postural or orthostatic hypotension, resulting in dizziness or fainting upon standing up [17] urinary incontinence or urinary retention [18] [19 ...
Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
The primary differentiating characteristic of Pure autonomic failure is decreased circulation and synthesis of norepinephrine, and dysfunction localized peripherally. It is relevant to note that progression to central nervous system neurodegeneration can also occur.
Autonomic dysreflexia (AD) is a life-threatening medical emergency characterized by hypertension and cardiac arrhythmias. [1] This condition is sometimes referred to as autonomic hyperreflexia. [ 2 ] Most cases of AD occur in individuals with spinal cord injuries. [ 3 ]
Sudomotor dysfunction is one of the most common and earliest neurophysiological manifestations of small fiber neuropathies. [3] In some instances, the small fibers of the autonomic nervous system can be affected, leading to urinary or bowel problems, episodes of rapid heartbeat (palpitations), dry eyes or mouth, or abnormal sweating.