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Triple-negative breast cancer (TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor is negative on all three tests giving the name triple-negative). [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process.
Breast lump, breast tumor: A breast lump associated with an inverted nipple and skin dimpling. Underlying cause was breast cancer. Specialty: Gynecology, General Surgery: Symptoms: An area of the breast that feel different than the surrounding tissue [1] Causes: Fibrocystic change, fibroadenomas, breast infection, galactoceles, breast cancer [1 ...
A Krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast. [1] Gastric adenocarcinoma, especially at the pylorus , is the most common source. [ 2 ]
A palpable tumor is not always found as it would be in other forms of breast cancer. Symptoms may include: Sudden swelling of the breast; Skin changes on breast; Reddened area with a texture resembling the peel of an orange (peau d'orange) Nipple retraction (flattened look) or discharge; Pain in the breast; Itching of breast
The prognosis of phyllodes tumor is good with an overall 87% 10-year survival rate. [5] After wide-margin surgical excision, 98.7% of benign phyllodes tumors and 80% of borderline were cured. [25] In rare cases where the tumor has metastasized, the prognosis is poor. [5] This most commonly occurs in cases of malignant grade phyllodes tumor. [5]
Some examples of adverse effects of core needle biopsies can include rare biopsy risks like infection, abscess formation, fistula formation, migration of any markers placed in the breast, and potential seeding of the tumor (causing displacement of cancer cells due to the procedure that can start new tumors elsewhere).