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Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3]
A few years after the discovery that selegiline was a selective MAO-B inhibitor, two Parkinson's disease researchers based in Vienna, Peter Riederer and Walther Birkmayer, realized that selegiline could be useful in Parkinson's disease. One of their colleagues, Moussa B. H. Youdim, visited Knoll in Budapest and took selegiline from him to ...
Parkinson-plus syndromes are usually more rapidly progressive and less likely to respond to antiparkinsonian medication than PD. [10] [11] However, the additional features of the diseases may respond to medications not used in PD. [citation needed] Current therapy for Parkinson-plus syndromes is centered around a multidisciplinary treatment of ...
Crazy Shirts is an American T-shirt and clothing company established in 1964 and based in Honolulu, Hawaii. The company operates 35 retail stores in Hawaii, California, Florida, Nevada, and Colorado. Crazy Shirts houses the largest printing facility in Hawaiʻi, on the island of Oʻahu, and employs more than 400 employees.
Compulsive buying can also be found among people with Parkinson's disease [3] or frontotemporal dementia. [4] [5] Compulsive buying-shopping disorder is classified by the ICD-11 among "other specified impulse control disorders". [5] Several authors have considered compulsive shopping rather as a variety of dependence disorder. [6]
A woman wearing a pink V-neck T-shirt T-shirt day in Leipzig, Germany. A T-shirt (also spelled tee shirt, or tee for short) is a style of fabric shirt named after the T shape of its body and sleeves. Traditionally, it has short sleeves and a round neckline, known as a crew neck, which lacks a collar. T-shirts are generally made of stretchy ...
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Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions. [27]
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