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The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ. NSG branded mice are among the most immunodeficient described to date. [1] NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. [2]
The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by Clarence Cook Little in 1929. [2] It employs over 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, Connecticut; Shanghai, China; and Yokohama, Japan. [3]
Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
Cote earned a BA in Chemistry and a BS in Biology from the University of California, Irvine in 1976, followed by an MD from the University of Chicago in 1980. He completed a surgical internship at the University of Michigan (1980-1981), pursued a pathology residency at Cornell University (1985-1987), and held several fellowships at Memorial Sloan Kettering Cancer Center between 1981 and 1990 ...
Before joining The Jackson Laboratory, he was the founding executive director of the Genome Institute of Singapore (GIS) (an A*STAR institute), chairman of the board of the Health Sciences Authority, and president of the Human Genome Organization (HUGO) (2007-2013). As the executive director of the GIS, he brought the institution to ...
The Jackson Laboratory was (and still is) the world's mecca for mouse genetics. From 1933 to 1934, Snell was a teacher at Washington University in St. Louis . After brief stints as teachers, in 1935 Snell joined the staff of The Jackson Laboratory in Bar Harbor on Mount Desert Island on the coast of Maine and he remained there for the entire ...
The 13 institutions participating in the Maine INBRE are the MDI Biological Laboratory as lead institution, The Jackson Laboratory, Bowdoin, Bates, and Colby Colleges, College of the Atlantic, the University of Maine, the University of Maine Honors College, and the University of Maine at Farmington, Fort Kent, Machias, and Presque Isle, and ...
A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. [1] Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics.