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The glomerulus receives its blood supply from an afferent arteriole of the renal arterial circulation. Unlike most capillary beds, the glomerular capillaries exit into efferent arterioles rather than venules. The resistance of the efferent arterioles causes sufficient hydrostatic pressure within the glomerulus to provide the force for ...
Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. [1] Bowman's capsule filters the blood , retaining large molecules such as proteins while smaller molecules such as water , salts , and sugars are filtered as the first step in the formation of urine .
Each glomerulus receives its blood supply from an afferent arteriole of the renal circulation. The glomerular blood pressure provides the driving force for water and solutes to be filtered out of the blood plasma, and into the interior of Bowman's capsule, called Bowman's space. Only about a fifth of the plasma is filtered in the glomerulus.
It stimulates erythropoiesis (production of red blood cells) in the bone marrow. Calcitriol, the activated form of vitamin D, promotes intestinal absorption of calcium and the renal reabsorption of phosphate. Renin is an enzyme which regulates angiotensin and aldosterone levels.
It stimulates erythropoiesis (production of red blood cells) in the bone marrow. Calcitriol, the activated form of vitamin D, promotes intestinal absorption of calcium and the renal reabsorption of phosphate. Renin is an enzyme which regulates angiotensin and aldosterone levels.
The macula densa is a collection of densely packed epithelial cells at the junction of the thick ascending limb (TAL) and distal convoluted tubule (DCT). As the TAL ascends through the renal cortex, it encounters its own glomerulus, bringing the macula densa to rest at the angle between the afferent and efferent arterioles.
54631 Ensembl ENSG00000161270 ENSMUSG00000006649 UniProt O60500 Q9QZS7 RefSeq (mRNA) NM_004646 NM_019459 RefSeq (protein) NP_004637 NP_062332 Location (UCSC) Chr 19: 35.83 – 35.87 Mb Chr 7: 30.16 – 30.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. The renal filtration barrier consists ...
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).