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The glomerulus receives its blood supply from an afferent arteriole of the renal arterial circulation. Unlike most capillary beds, the glomerular capillaries exit into efferent arterioles rather than venules. The resistance of the efferent arterioles causes sufficient hydrostatic pressure within the glomerulus to provide the force for ...
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
Each glomerulus receives its blood supply from an afferent arteriole of the renal circulation. The glomerular blood pressure provides the driving force for water and solutes to be filtered out of the blood plasma, and into the interior of Bowman's capsule, called Bowman's space. Only about a fifth of the plasma is filtered in the glomerulus.
The macula densa is a collection of densely packed epithelial cells at the junction of the thick ascending limb (TAL) and distal convoluted tubule (DCT). As the TAL ascends through the renal cortex, it encounters its own glomerulus, bringing the macula densa to rest at the angle between the afferent and efferent arterioles.
54631 Ensembl ENSG00000161270 ENSMUSG00000006649 UniProt O60500 Q9QZS7 RefSeq (mRNA) NM_004646 NM_019459 RefSeq (protein) NP_004637 NP_062332 Location (UCSC) Chr 19: 35.83 – 35.87 Mb Chr 7: 30.16 – 30.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. The renal filtration barrier consists ...
It stimulates erythropoiesis (production of red blood cells) in the bone marrow. Calcitriol, the activated form of vitamin D, promotes intestinal absorption of calcium and the renal reabsorption of phosphate. Renin is an enzyme which regulates angiotensin and aldosterone levels.
It stimulates erythropoiesis (production of red blood cells) in the bone marrow. Calcitriol, the activated form of vitamin D, promotes intestinal absorption of calcium and the renal reabsorption of phosphate. Renin is an enzyme which regulates angiotensin and aldosterone levels.
A. The endothelial cells of the glomerulus; 1. pore (fenestra). B. Glomerular basement membrane: 1. lamina rara interna 2. lamina densa 3. lamina rara externa C. Podocytes: 1. enzymatic and structural protein 2. filtration slit 3. diaphragma. Podocytes have primary processes called trabeculae, which wrap around the glomerular capillaries. [2]
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