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Letrozole is contraindicated in women having a pre-menopausal hormonal status. Precautions are advised against becoming pregnant while using letrozole; on the loss of bone mineral density; on the increased level of cholesterol and fat in the blood; and on dizziness and against driving. [22] Breast feeding (lactation) is also counterindicated. [23]
PPIs may induce common side effects including headache, diarrhoea, abdominal pain, and nausea. Taking PPI may rarely cause community-acquired pneumonia . Prolonged use of PPI may be associated with intestinal Clostridioides difficile infection , low magnesium level , Vitamin B12 and iron deficiency, osteoporosis , acute kidney inflammation, and ...
The first aromatase inhibitor that was discovered was aminoglutethimide, classified as first-generation AIs. It is still used today despite causing side effects such as lack of target enzyme specificity which also has effects on other cytochrome P450 enzymes. [12] Furthermore, it affects the synthesis of aldosterone, thyroid hormone and ...
Pneumococcal pneumonia is a type of bacterial pneumonia that is caused by Streptococcus pneumoniae (pneumococcus). [1] It is the most common bacterial pneumonia found in adults, the most common type of community-acquired pneumonia, and one of the common types of pneumococcal infection. The estimated number of Americans with pneumococcal ...
[13] [15] Pneumonia is also the leading cause of death in children less than five years of age in low income countries. [15] The most common cause of pneumonia is pneumococcal bacteria, Streptococcus pneumoniae accounts for 2/3 of bacteremic pneumonias. [16] Invasive pneumococcal pneumonia has a mortality rate of around 20%. [14]
The field of pharmacotoxicology also involves the treatment and prevention of pharmaceutically induced side effects. Pharmacotoxicology can be separated into two different categories: pharmacodynamics (the effects of a drug on an organism), and pharmacokinetics (the effects of the organism on the drug).
Chemical pneumonitis is inflammation of the lung caused by aspirating or inhaling irritants. [1] It is sometimes called a "chemical pneumonia", though it is not infectious.. There are two general types of chemical pneumonitis: acute and chron
Atypical bacteria causing pneumonia are Coxiella burnetii, Chlamydophila pneumoniae (), Mycoplasma pneumoniae (), and Legionella pneumophila.. The term "atypical" does not relate to how commonly these organisms cause pneumonia, how well it responds to common antibiotics or how typical the symptoms are; it refers instead to the fact that these organisms have atypical or absent cell wall ...