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Glycosuria leads to excessive water loss into the urine with resultant dehydration, a process called osmotic diuresis. Alimentary glycosuria is a temporary condition, when a high amount of carbohydrate is taken, it is rapidly absorbed in some cases where a part of the stomach is surgically removed, the excessive glucose appears in urine ...
Renal glycosuria is a rare condition in which the simple sugar glucose is excreted in the urine [1] despite normal or low blood glucose levels. With normal kidney (renal) function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood.
If glucose is not reabsorbed by the kidney, it appears in the urine, in a condition known as glycosuria. This is associated with diabetes mellitus. [1] Firstly, the glucose in the proximal tubule is co-transported with sodium ions into the proximal convoluted tubule walls via the SGLT2 cotransporter. Some (typically smaller) amino acids are ...
If the renal threshold itself is reduced, can also produce detectable glucose in the urine. This is called renal glycosuria. [2] Taken together, the collection of a kidney's renal thresholds essentially define much of its function in renal physiology. Many tests of kidney function amount to measures of renal thresholds for various substances.
Dehydration due to glycosuria and osmotic diuresis; Increased thirst 'Fruity' smelling breath odor; Sweet sensation that is felt into the mouth without a reason; Nausea and vomiting; Abdominal pain; Impairment of cognitive function, along with increased sadness and anxiety [18] [19] Weight loss
[1] pRTA also has several causes, and may occasionally be present as a solitary defect, but is usually associated with a more generalised dysfunction of the proximal tubular cells called Fanconi syndrome where there is also phosphaturia, glycosuria, aminoaciduria, uricosuria and tubular proteinuria.
The presence of glucose in the urine is known as glycosuria. In people with normal blood sugar levels, the amount of glucose in the urine should be negligible as it is reabsorbed by the renal tubules. [72] High blood sugar levels (hyperglycemia) cause excess glucose to spill over into the urine and result in a positive reading.
Application of this name to DI arose from the fact that diabetes insipidus does not cause glycosuria (excretion of glucose into the urine). In a large survey conducted amongst patients with central diabetes insipidus, the majority were in favor of changing the disease's name to "vasopressin deficiency" to avoid confusion with diabetes mellitus. [6]