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Prednisolone was discovered and approved for medical use in 1955. [10] It is on the World Health Organization's List of Essential Medicines. [11] It is available as a generic drug. [6] In 2022, it was the 136th most commonly prescribed medication in the United States, with more than 4 million prescriptions. [12] [13]
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
have a density of approximately 1.2 to 1.5 g cm −3 (approximately that of the drug to be suspended or dissolved) [16] have a vapour pressure of 40 to 80 psig [18] have no toxicity to the patient [16] [18] be non-flammable [16] [18] be able to dissolve common additives (active ingredients should be either fully soluble or fully insoluble) [16]
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
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Prednisone is a synthetic pregnane corticosteroid and derivative of cortisone and is also known as δ 1-cortisone or 1,2-dehydrocortisone or as 17α,21-dihydroxypregna-1,4-diene-3,11,20-trione. [42] [43]
Then change to oral hydrocortisone or cortisone as a single morning dose, and gradually decrease by 2.5 mg each week. When the morning dose is less than replacement, the return of normal basal adrenal function may be documented by checking 0800 cortisol levels prior to the morning dose; stop drugs when 0800 cortisol is 10 μg/dl.
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