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Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis, [1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature. [2]
Due to the recycling problem of phosphoryl chloride, SW was adopted in step three of the DMHP process in the preparation of Sarin. [5] SW was also adopted as a standard precursor to V agents, having been used to prepare QL for unitary and binary VX. SW was the first agent adopted to prepare VX in one pot reaction by aqueous medium. [6]
It will react with thionyl chloride to produce methylphosphonic acid dichloride, which is used in the production of sarin and soman nerve agents. Various amines can be used to catalyse this process. [3] It can be used as a sarin-simulant for the calibration of organophosphorus detectors.
"A novel Cu(OTf) 2 mediated three component high yield synthesis of α-aminophosphonates" (PDF). Arkivoc (1838EP): 183– 9. [permanent dead link ] Singh R, Nolan SP (November 2005). "Synthesis of phosphorus esters by transesterification mediated by N-heterocyclic carbenes (NHCs)". Chemical Communications (43): 5456– 8. doi:10.1039 ...
Methylphosphonic acid is an organophosphorus compound with the chemical formula CH 3 P(O)(OH) 2. The phosphorus center is tetrahedral and is bonded to a methyl group, two OH groups and an oxygen. Methylphosphonic acid is a white, non-volatile solid that is poorly soluble in organic solvent but soluble in water and common alcohols.
Organic synthesis is a special type of chemical synthesis dealing with the synthesis of organic compounds. For the total synthesis of a complex product, multiple procedures in sequence may be required to synthesize the product of interest, needing a lot of time. A purely synthetic chemical synthesis begins with basic lab compounds.
N,N′-Dicyclohexylcarbodiimide (DCC or DCCD) [1] is an organic compound with the chemical formula (C 6 H 11 N) 2 C. It is a waxy white solid with a sweet odor. Its primary use is to couple amino acids during artificial peptide synthesis.
Methylphosphonyl difluoride (DF), also known as EA-1251 [2] or difluoro, [3] is a chemical weapon precursor. Its chemical formula is CH 3 POF 2.It is a Schedule 1 substance under the Chemical Weapons Convention.