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Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 28 ]
Economic integration with the rest of the world becomes easier as a result of lowered transaction costs and stabler prices. [2] Rose (2000) applied the gravity model of trade and provided empirical evidence that countries sharing a common currency engage in significantly increased trade among them, and that the benefits of currency substitution ...
Bristol-Myers Squibb and Pfizer Announce Publication of ARISTOTLE Subanalysis in Circulation Subgroup analysis demonstrates that the treatment effects of Eliquis ® (apixaban) vs. warfarin, across ...
In the late 1970s, South Africa was involved in an international controversy over apartheid and the South African Border War in Angola. As a result, it was subject to an international arms embargo and had to, out of necessity, design and manufacture its own weapons. [1] The SS-77 was developed to replace the FN MAG. It was designed in 1977 by ...
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A barrier to switching is then formed as swapping internet services providers is a time consuming effort. [3] Switching cost or switching barriers are the expenses or cost that a consumer incurs due to the result of changing brand, suppliers, or products. Although most common switching cost is in monetary in nature, there are also psychological ...
Local number portability (LNP) for fixed lines, and full mobile number portability (FMNP) for mobile phone lines, refers to the ability of a "customer of record" of an existing fixed-line or mobile telephone number assigned by a local exchange carrier (LEC) to reassign the number to another carrier ("service provider portability"), move it to another location ("geographic portability"), or ...
INR self-monitoring is a medical kit that is used by patients both on long-term and on lifetime anti-coagulation therapy to measure their INR (International Normalized Ratio) levels themselves at your premises without going to a clinic. People who self-monitor their INR levels use a portable INR monitor as in a clinic.