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  2. Buprenorphine/naloxone - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine/naloxone

    Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder , and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl ).

  3. Ceiling effect (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Ceiling_effect_(pharmacology)

    Mixed agonist-antagonist opioids, such as nalbuphine, serve as a classic example of the ceiling effect; increasing the dose of a narcotic frequently leads to smaller and smaller gains in relief of pain. In many cases, the severity of side effects from a medication increases as the dose increases, long after its therapeutic ceiling has been reached.

  4. Drug titration - Wikipedia

    en.wikipedia.org/wiki/Drug_titration

    Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [1] When a drug has a narrow therapeutic index, titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [2]

  5. Buprenorphine - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine

    Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant.

  6. Azithromycin - Wikipedia

    en.wikipedia.org/wiki/Azithromycin

    The recommended dosage for controlling asthma exacerbations with azithromycin is either 500 mg or 250 mg taken orally as tablets three times a week. In adults with severe asthma, low-dose azithromycin may be prescribed as an add-on treatment when standard therapies such as inhaled corticosteroids or long-acting beta2-agonists are not sufficient ...

  7. RSV vaccine side effects in older adults . The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache ...

  8. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    Type A reactions are dosage (concentration) dependent. Usually, this kind of side effect is an extension of an ongoing treatment. Pharmacokinetics and pharmacodynamics are termed toxicokinetics and toxicodynamics in the field of ecotoxicology. Here, the focus is on toxic effects on a wide range of organisms.

  9. Serotonin syndrome - Wikipedia

    en.wikipedia.org/wiki/Serotonin_syndrome

    A postulated "spectrum concept" of serotonin toxicity emphasises the role that progressively increasing serotonin levels play in mediating the clinical picture as side effects merge into toxicity. The dose-response relationship is the effect of progressive elevation of serotonin, either by raising the dose of one drug, or combining it with ...

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