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An article published by the journal Nature on 6 July 2021 cited data released by the United Arab Emirates on some 81,000 individuals who had received Sputnik V, according to which the vaccine demonstrated an efficacy of 97.8% in preventing symptomatic COVID-19, and 100% efficacy in preventing severe complications.
A vaccine is generally considered effective if the estimate is ≥50% with a >30% lower limit of the 95% confidence interval. [6] As of September 2021, no study on Sputnik Light reported confidence intervals, so it is not possible to know the accuracy of the estimates. Effectiveness is generally expected to slowly decrease over time. [7]
In addition, vaccine developers have been criticized for aggressively advertising their vaccine efficacy prior to the completion of phase III clinical trial. The most substantial criticism came from Dr. Konstantin Chumakov, who currently serves as the associate director for Research at the FDA Office of Vaccines Research and Review.
On 11 August 2020, President Putin said in a meeting that the Sputnik V vaccine (registered as Gam-COVID-Vac) developed by the Gamaleya Research Institute of Epidemiology and Microbiology was the first vaccine against the coronavirus to be registered.
Vaccine Initial effectiveness by severity of COVID-19 Study location Refs Asymptomatic Symptomatic Hospitalization Death Oxford–AstraZeneca
The WHO has implemented an "Effective Vaccine Management" system, [192] which includes constructing priorities to prepare national and subnational personnel and facilities for vaccine distribution, including: Trained staff to handle time- and temperature-sensitive vaccines; Robust monitoring capabilities to ensure optimal vaccine storage and ...
Vaccine efficacy is the reduction in risk of getting the disease by vaccinated participants in a controlled trial compared with the risk of getting the disease by unvaccinated participants. [346] An efficacy of 0% means that the vaccine does not work (identical to placebo).
Influenza Vaccine. Vaccine efficacy or vaccine effectiveness is the percentage reduction of disease cases in a vaccinated group of people compared to an unvaccinated group.For example, a vaccine efficacy or effectiveness of 80% indicates an 80% decrease in the number of disease cases among a group of vaccinated people compared to a group in which nobody was vaccinated.