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  2. Mitophagy - Wikipedia

    en.wikipedia.org/wiki/Mitophagy

    Mitophagy impaired due to the deletion of autophagy-related genes led to a loss of HSC function, more likely as a result of mitochondrial damage that stimulated excessive ROS production. On the contrary, mitophagy induction appeared to be protective for HSC and directed stem cell differentiation to the myeloid lineage. [22]

  3. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

    www.aol.com/terrible-amazing-side-effects-weight...

    GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now. GLP-1s ...

  4. Weight Loss Injections: What You Need to Know, From ... - AOL

    www.aol.com/weight-loss-injections-know-costs...

    Side Effects and Risks of Weight Loss Injections. Even though GLP-1s and GIP/GLP-1s are safe for most people, there are some side effects to keep in mind. The most common side effects are ...

  5. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

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    There’s been lots of attention on type 2 diabetes drugs recently, especially since they might also be able to support weight loss. Whether you have type 2 diabetes or obesity, you may have heard ...

  6. Autophagy - Wikipedia

    en.wikipedia.org/wiki/Autophagy

    Autophagy degrades damaged organelles, cell membranes and proteins, and insufficient autophagy is thought to be one of the main reasons for the accumulation of damaged cells and aging. [87] Autophagy and autophagy regulators are involved in response to lysosomal damage, often directed by galectins such as galectin-3 and galectin-8.

  7. HDAC6 - Wikipedia

    en.wikipedia.org/wiki/HDAC6

    Since HDAC6 is dysregulated and/or implicated in several cancers and neurodegenerative disorders, pharmacological inhibition of this specific enzyme holds great therapeutic potential and could also limit side effects associated with pan-inhibitors of multiple HDAC enzymes. [7]

  8. Comparing Oral vs. Injectable Semaglutide: Is One More ... - AOL

    www.aol.com/comparing-oral-vs-injectable...

    Research sponsored by Novo Nordisk in patients with type 2 diabetes found that, together with diet and exercise, Ozempic led to an average weight loss of almost 10 pounds, while Rybelsus led to an ...

  9. Autophagosome - Wikipedia

    en.wikipedia.org/wiki/Autophagosome

    Atg1 is a kinase upregulated upon induction of autophagy. Atg13 regulates Atg1 and together they form a complex called Atg13:Atg1, which receives signals from the master of nutrient sensing – Tor. Atg1 is also important in late stages of autophagosome formation. [8]

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