Search results
Results from the WOW.Com Content Network
The Z-factor defines a characteristic parameter of the capability of hit identification for each given assay. The following categorization of HTS assay quality by the value of the Z-Factor is a modification of Table 1 shown in Zhang et al. (1999); [2] note that the Z-factor cannot exceed one.
Signal-to-background ratio, signal-to-noise ratio, signal window, assay variability ratio, and Z-factor have been adopted to evaluate data quality. [9] [12] Strictly standardized mean difference has recently been proposed for assessing data quality in HTS assays. [13] [14]
The advantage of the Z-factor over the S/N and S/B is that it takes into account the variabilities in both compared groups. As a result, the Z-factor has been broadly used as a QC metric in HTS assays. [citation needed] The absolute sign in the Z-factor makes it inconvenient to derive its statistical inference mathematically.
In the case of TRF assays, a wash step is required to remove unbound fluorescent reagents prior to measuring the activity signal of the assay. This increases reagent use, time to complete the assay, and limits the ability to miniaturize the system (e.g. converting from a 384-well microtiter plate to a 1536-well plate). [5]
Z-score is a type of statistical ratio. It may also refer to: Z-value, in ecology; Z-factor, in high-throughput screening; Altman Z-score, in financial analysis
The Warburg–Christian method is an ultraviolet spectroscopic protein and nucleic acid assay method based on the absorbance of UV light at 260 nm and 280 nm wavelengths. . Proteins generally absorb light at 280 nanometers due to the presence of tryptophan and ty
Get answers to your AOL Mail, login, Desktop Gold, AOL app, password and subscription questions. Find the support options to contact customer care by email, chat, or phone number.
The z-test for comparing two proportions is a statistical method used to evaluate whether the proportion of a certain characteristic differs significantly between two ...