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Steroid-induced osteoporosis is osteoporosis arising from the use of glucocorticoids (a class of steroid hormones) analogous to Cushing's syndrome but involving mainly the axial skeleton. The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake.
Causes: Medications related to cancer therapy, and osteoporosis in combination with dental surgery: Risk factors: Duration of anti-resorptive or anti-angiogenic drugs, intravenous vs by-mouth: Diagnostic method: Exposed bone >8 weeks: Differential diagnosis: Osteomyelitis, Osteoradionecrosis: Prevention: No definitive. Drug holiday for some ...
Vitamin D regulates proconvulsant and anticonvulsant factors. More specifically, Vitamin D is involved in the down regulation of cytokine IL-6, which is a proconvulsant. [7] Additionally, vitamin D is associated with the up regulation of neurotrophic factors: GDNF and TN3. These neurotrophic factors are anticonvulsant. In the absence or ...
Anticonvulsants suppress the excessive rapid firing of neurons during seizures. [6] Anticonvulsants also prevent the spread of the seizure within the brain. [7] Conventional antiepileptic drugs may block sodium channels or enhance γ-aminobutyric acid function. Several antiepileptic drugs have multiple or uncertain mechanisms of action. [8]
Likewise, postmenopausal women taking anticonvulsants have a greater risk of fracture than their drug-naive counterparts. [33] Anticonvulsants affect the bones in many ways. They cause hypophosphatemia, hypocalcemia, low vitamin D levels, and increased parathyroid hormone. Anticonvulsants also contribute to the increased rate of fractures by ...
Until the anticonvulsant medication leaves your system, you’re not going to escape the common side effects. Gabapentin has a half-life of around five to seven hours and takes two days on average ...
Many other drugs including common antibiotics may cause bone marrow suppression. Unlike chemotherapy the effects may not be due to direct destruction of stem cells but the results may be equally serious. The treatment may mirror that of chemotherapy-induced myelosuppression or may be to change to an alternate drug or to temporarily suspend ...
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .