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The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene. [5] [6] Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. [7]
The cell division cycle protein 20 homolog is an essential regulator of cell division that is encoded by the CDC20 gene [5] [6] in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase.
66214 Ensembl ENSG00000102760 ENSMUSG00000022018 UniProt Q9H4X1 Q9DBX1 RefSeq (mRNA) NM_014059 NM_025427 RefSeq (protein) NP_054778 NP_079703 Location (UCSC) Chr 13: 41.46 – 41.47 Mb Chr 14: 79.53 – 79.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Regulator of cell cycle RGCC (RGCC) also known as response gene to complement 32 protein (RGC-32) is a protein that in humans is ...
Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene ( c yc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism.
Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. [5] [6] The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication.
Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene. [5] [6] [7] The Cdc7 kinase is involved in regulation of the cell cycle at the point of chromosomal DNA replication. [8] The gene CDC7 appears to be conserved throughout eukaryotic evolution; this means that most eukaryotic cells have the Cdc7 ...
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells.