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Overweight female dogs are especially prone to developing these tumors, and most older or overweight dogs have at least one lipoma. [46] [47] In dogs, lipomas usually occur in the trunk or upper limbs. [45] They are also found less commonly in cattle and horses, and rarely in cats and pigs. [47] [48] However, a pedunculated lipoma can cause ...
Differentially, any other skin tumor of the dog can be considered: In the skin especially histiocytomas, basaliomas, melanomas and T-cell lymphomas, in the subcutis especially lipomas, hemangiopericytomas and hemangiosarcomas. However, the differentiation of these tumors hardly causes any problems in cytodiagnostics.
In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15, where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [2] This is one of the most commonly found mutations in solitary lipomatous tumors but lipomas often have multiple mutations. Reciprocal translocations involving chromosomes 12q13 and 12q14 ...
Dog with atopic dermatitis, with signs around the eye created by rubbing. Atopy is a hereditary [3] and chronic (lifelong) allergic skin disease. Signs usually begin between 6 months and 3 years of age, with some breeds of dog, such as the golden retriever, showing signs at an earlier age.
However, in dogs affected by an autoimmune disease, the immune system loses the ability to make this distinction, causing the immune system to attack the body. [5] Autoimmune diseases in the base layer of the epidermis are characterized by damage to the connective tissue and vesicle formation located below the epidermis layer and the dermis ...
Venereal granulomata on a dog's penis. A canine transmissible venereal tumor (CTVT), also known as a transmissible venereal tumor (TVT), canine transmissible venereal sarcoma (CTVS), sticker tumor and infectious sarcoma, is a histiocytic tumor of the external genitalia of the dog and other canines, and is transmitted from animal to animal during mating.
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Disseminated mastocytosis is rarely seen in young dogs and cats, while mast cell tumors are usually skin tumors in older dogs and cats. Although not always malignant, they do have the potential to be. Up to 25 percent of skin tumors in dogs are mast cell tumors, [1] with a similar number in cats. [2]
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