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The Electronic Medicines Compendium is a provider of information on medicines, produced by Datapharm. It lists summaries of product characteristics and patient information leaflets. [1][2]
Medication package insert. A package insert is a document included in the package of a medication that provides information about that drug and its use. For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the drug. Package inserts for prescription drugs often include a ...
The Summary of Product Characteristics provided in the electronic Medicines Compendium [eMC [16]] further lists common and uncommon adverse reactions that have been reported for Lemtrada, which include serious opportunistic nocardial infections and cytomegalovirus syndrome. [17] [18] [19]
Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic, such as furosemide. [6] It is given by mouth or by injection into a vein. [5]
Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [ 9 ] It has also been used in alcohol dependence and essential tremor. [ 9 ] For epilepsy this includes treatment for generalized or focal seizures. [ 10 ] It is taken orally (by mouth).
Valproate (valproic acid, VPA, sodium valproate, and valproate semisodium forms) are medications primarily used to treat epilepsy and bipolar disorder and prevent migraine headaches. [ 7 ] They are useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. [ 7 ]
Zonisamide is approved in the United States, [2] [12] and United Kingdom [13] for adjunctive treatment of partial seizures in adults and Japan for both adjunctive and monotherapy for partial seizures (simple, complex, secondarily generalized), generalized (tonic, tonic-clonic (grand mal), and atypical absence) and combined seizures. [14]
This combination is produced by an Iranian company under the trade name of Sovodak. [6] The combination includes 400 mg sofosbuvir and 60 mg daclatasvir and has been used in clinical trials since 2015.