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An acid–base titration is a method of quantitative analysis for determining the concentration of Brønsted-Lowry acid or base (titrate) by neutralizing it using a solution of known concentration (titrant). [1] A pH indicator is used to monitor the progress of the acid–base reaction and a titration curve can be constructed.
In a buffer, a weak acid and its conjugate base (in the form of a salt), or a weak base and its conjugate acid, are used in order to limit the pH change during a titration process. Buffers have both organic and non-organic chemical applications. For example, besides buffers being used in lab processes, human blood acts as a buffer to maintain pH.
Acids and bases. The Brønsted–Lowry theory (also called proton theory of acids and bases[1]) is an acid–base reaction theory which was first developed by Johannes Nicolaus Brønsted and Thomas Martin Lowry independently in 1923. [2][3] The basic concept of this theory is that when an acid and a base react with each other, the acid forms ...
Neutralization (chemistry) Animation of a strong acid–strong base neutralization titration (using phenolphthalein). The equivalence point is marked in red. In chemistry, neutralization or neutralisation (see spelling differences) is a chemical reaction in which acid and a base react with an equivalent quantity of each other.
Titration. A burette and Erlenmeyer flask (conical flask) being used for an acid–base titration. Titration (also known as titrimetry[1] and volumetric analysis) is a common laboratory method of quantitative chemical analysis to determine the concentration of an identified analyte (a substance to be analyzed).
The Henderson–Hasselbalch equation relates the pH of a solution containing a mixture of the two components to the acid dissociation constant, K a of the acid, and the concentrations of the species in solution. [2] Simulated titration of an acidified solution of a weak acid (pK a = 4.7) with alkali
In Figure 1, the effect is illustrated by the simulated titration of a weak acid with pK a = 4.7. The relative concentration of undissociated acid is shown in blue, and of its conjugate base in red. The pH changes relatively slowly in the buffer region, pH = pK a ± 1, centered at pH = 4.7, where [HA] = [A −]. The hydrogen ion concentration ...
e. Acid–base extraction is a subclass of liquid–liquid extractions and involves the separation of chemical species from other acidic or basic compounds. [1] It is typically performed during the work-up step following a chemical synthesis to purify crude compounds [2] and results in the product being largely free of acidic or basic impurities.