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Resolution in the context of structural biology is the ability to distinguish the presence or absence of atoms or groups of atoms in a biomolecular structure. Usually, the structure originates from methods such as X-ray crystallography, electron crystallography, or cryo-electron microscopy. The resolution is measured of the "map" of the ...
Paper chromatography is a technique that involves placing a small dot or line of sample solution onto a strip of chromatography paper. The paper is placed in a container with a shallow layer of solvent and sealed. As the solvent rises through the paper, it meets the sample mixture, which starts to travel up the paper with the solvent.
The design of experiments (DOE or DOX), also known as experiment design or experimental design, is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design introduces conditions that ...
The resolution that can be achieved with in situ Hi-C can be up to 950 to 1000 bp compared to the 1 to 10 Mb resolution of standard Hi-C and the 100 kb resolution of DNase Hi-C. [3] [4] [14] [19] While standard Hi-C makes use of a 6-bp cutter such as HindIII for the restriction digest step, in situ Hi-C uses a 4-bp cutter such as MboI or its ...
Resolution (chromatography) Example chromatogram showing signal as a function of retention time. In chromatography, resolution is a measure of the separation of two peaks of different retention time t in a chromatogram. [1][2][3][4]
A scientific theory is a well-substantiated explanation of some aspect of the natural world, based on a body of facts that have been repeatedly confirmed through observation and experiment. Such fact-supported theories are not "guesses" but reliable accounts of the real world. The theory of biological evolution is more than "just a theory".
IUPAC definition. The IUPAC definition for resolution in mass spectrometry is. Where a larger resolution indicates a better separation of peaks. [1][2] This definition is used in a number of mass spectrometry texts. [3][4][5][6][7][8][9][10][11] This use is also implied by the term "high-resolution mass spectrometry." [12]
Atomic force microscopy [1] (AFM) is a type of SPM, with demonstrated resolution on the order of fractions of a nanometer, more than 1000 times better than the optical diffraction limit. The information is gathered by "feeling" or "touching" the surface with a mechanical probe.