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A cat hair showing agouti coloration A domestic rabbit with agouti coloration. Agouti is a type of fur coloration in which each hair displays two or more bands of pigmentation. [1] [2] The overall appearance of agouti fur is usually gray or dull brown, [3] although dull yellow is also possible.
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
According to Candille, et al. (2007), dog coat color can largely be explained by three genes: MC1R, Agouti and CBD103. When a dog has wild-type alleles at all three genes, it will have a yellow coat. When the dog has a loss-of-function allele at MC1R, it will have a yellow coat regardless of the genes it carries on the other two genes. Only a ...
A Labrador exhibiting a yellow coat colour. Domestic dogs exhibit diverse coat colours and patterns.In many mammals, different colour patterns are the result of the regulation of the Agouti gene, which can cause hair follicles to switch from making black or brown pigments to yellow or nearly white pigments.
The agouti (/ ə ˈ ɡ uː t iː / ⓘ, ə-GOO-tee) or common agouti is many of several rodent species of the genus Dasyprocta. They are native to Central America , northern and central South America , and the southern Lesser Antilles .
Many colors are possible, but all variations are produced by changes in only a few genes. Bay is the most common color of horse, [2] followed by black and chestnut. A change at the agouti locus is capable of turning bay to black, while a mutation at the extension locus can turn bay or black to chestnut.
Agouti (coloration), fur coloration in which each hair has alternating dark and light bands; Agouti-signalling protein or ASIP, a circulating hormone encoded by the agouti gene that acts as an antagonist at melanocortin receptors; Agouti-related peptide, a neuropeptide produced in the brain by the AgRP/NPY neuron