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Diffuse cutaneous leishmaniasis produces widespread skin lesions which resemble leprosy, and may not heal on their own. [3] Mucocutaneous leishmaniasis causes both skin and mucosal ulcers with damage primarily of the nose and mouth. [2] [3] Visceral leishmaniasis or kala-azar ('black fever') is the most serious form and is generally fatal if ...
Mucocutaneous leishmaniasis is an especially disturbing form of cutaneous leishmaniasis, because it produces destructive and disfiguring lesions of the face. It is most often caused by Leishmania braziliensis, but cases caused by L. aethiopica have also been described. [10] Mucocutaneous leishmaniasis is very difficult to treat.
Mucocutaneous leishmaniasis infections start off as a reaction at the bite, and can go by metastasis into the mucous membrane and become fatal. L. braziliensis: Mucocutaneous infections are most common in Bolivia, Brazil and Peru. Mucocutaneous infections are also found in Karamay, China Xinjiang Uygur Autonomous Region.
Cutaneous leishmaniasis is commonly characterized with skin lesions, which can appear localized, or throughout the body. While mucocutaneous leishmaniasis is characterized with ulcers around the skin, mouth, and nose. This form of Leishmaniasis has also been known to can spread by metastasis and can be deadly. [2]
Leishmaniasis: Leishmania spp. cutaneous, mucocutaneous, or visceral: visual identification of lesion or microscopic stain with Leishman's or Giemsa's stain visceral leishmaniasis – worldwide; cutaneous leishmaniasis – Old World; mucocutaneous leishmaniasis – New World Phlebotomus, Lutzomyia – bite of several species of phlebotomine ...
Leishmania donovani is a species of intracellular parasites belonging to the genus Leishmania, a group of haemoflagellate kinetoplastids that cause the disease leishmaniasis. It is a human blood parasite responsible for visceral leishmaniasis or kala-azar, the most severe form of leishmaniasis.
Lifecycle of Leishmaniasis. The three forms of leishmaniasis, a protozoal disease, are visceral , cutaneous, and mucocutaneous. [54] There are an estimated 12 million people infected. [18] It is fatal if untreated, and 20,000 deaths from visceral leishmaniasis occur annually. [55]
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