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  2. Chronic venous insufficiency - Wikipedia

    en.wikipedia.org/wiki/Chronic_venous_insufficiency

    Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins, a treatable condition. [2]

  3. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    Unlike the other twelve vitamins, vitamin D is only conditionally essential - in a preindustrial society people had adequate exposure to sunlight and the vitamin was a hormone, as the primary natural source of vitamin D was the synthesis of cholecalciferol in the lower layers of the skin’s epidermis, triggered by a photochemical reaction with ...

  4. Lipodermatosclerosis - Wikipedia

    en.wikipedia.org/wiki/Lipodermatosclerosis

    The exact cause of lipodermatosclerosis is unknown. [3] [6] Venous disease, such as venous incompetence, venous hypertension, and body mass may be relevant to the underlying pathogenesis. [3] Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries.

  5. Bradykinin - Wikipedia

    en.wikipedia.org/wiki/Bradykinin

    Bradykinin (BK) (from Greek brady-'slow' + -kinin, kīn(eîn) 'to move') is a peptide that promotes inflammation.It causes arterioles to dilate (enlarge) via the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor and makes veins constrict, via prostaglandin F2, thereby leading to leakage into capillary beds, due to the increased pressure in the capillaries.

  6. This type of supplement may increase heart disease risk, new ...

    www.aol.com/news/type-supplement-may-increase...

    High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research.. The report, published Monday ...

  7. Varicose veins - Wikipedia

    en.wikipedia.org/wiki/Varicose_veins

    Varicose veins in the legs could be due to ovarian vein reflux. [19] [20] Both ovarian and internal iliac vein reflux causes leg varicose veins. This condition affects 14% of women with varicose veins or 20% of women who have had vaginal delivery and have leg varicose veins. [21]

  8. The best exercises to tone your legs – no weights required

    www.aol.com/news/25-bodyweight-exercises...

    Engage your abs and lower your right leg down until your knee almost touches the floor. Both knees should be at about a 90-degree angle. Step forward and repeat 10 times before switching sides.

  9. Endothelial dysfunction - Wikipedia

    en.wikipedia.org/wiki/Endothelial_dysfunction

    The main cause of endothelial dysfunction is impaired bioavailability of nitric oxide. [ 1 ] In addition to acting as a semipermeable membrane , the endothelium is responsible for maintaining vascular tone and regulating oxidative stress by releasing mediators, such as nitric oxide, prostacyclin and endothelin , and by controlling local ...

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