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Gepants have been suggested to have less pain relief at 2 hours compared to triptans. Similar to ditans, they offer another therapy option that does not include vasoconstriction, thus may be suitable for those with cardiovascular risk factors. [7] They are well tolerated with fewer adverse effects compared to triptans . [7]
Sumatriptan was the pioneer drug in this class. The second generation's triptans such as zolmitriptan, naratriptan, rizatriptan, almotriptan, eletriptan and frovatriptan soon became available. [18] Different triptans are available in different formulations and in different strengths (see table 2).
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Florida State University (FSU or Florida State) is a public research university in Tallahassee, Florida, United States. It is a senior member of the State University System of Florida and a preeminent university in the state. [15] Chartered in 1851, it is located on Florida's oldest continuous site of higher education. [16] [2]
Triptans have a wide variety of pharmacokinetic properties. Bioavailability is between 14% and 70%, biological half-life (T 1/2 ) is between 2 and 26 hours. Their good ability to cross the blood–brain barrier and the rather long half life of some triptans may result in lower frequencies of migraine recurrence.
Atogepant, sold under the brand name Qulipta among others, is a medication used to prevent migraines. [4] [5] It is a gepant, an orally active calcitonin gene-related peptide receptor antagonist.
The Donald L. Tucker Civic Center is a multi-purpose indoor arena located on the Florida State University campus in Tallahassee, Florida, United States. The arena has the biggest capacity of any arena in the Florida Panhandle. The arena opened in 1981 and was built at a cost of over $30 million, financed by the city.
This category includes various buildings and other structures located on the Florida State University campus in Tallahassee, Florida. For more information, see List of Florida State University buildings , History of Florida State University and Florida State University .