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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  3. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Warfarin is indicated for the prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism; [9] prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement; [9] and reduction in the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after ...

  4. Urea-containing cream - Wikipedia

    en.wikipedia.org/wiki/Urea-containing_cream

    Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. [5] Specific condition with hyperkeratosis where urea cream is useful include: Dry skin and rough skin [5] Dermatitis [5]

  5. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    The use of anticoagulants is a decision based on the risks and benefits of anticoagulation. [14] The biggest risk of anticoagulation therapy is the increased risk of bleeding. [ 15 ] In otherwise healthy people, the increased risk of bleeding is minimal, but those who have had recent surgery, cerebral aneurysms , and other conditions may have ...

  6. Management of acute coronary syndrome - Wikipedia

    en.wikipedia.org/wiki/Management_of_acute...

    Information card published by the National Heart, Lung, and Blood Institute urging people with symptoms of angina to call the emergency medical services.. Because of the relationship between the duration of myocardial ischemia and the extent of damage to heart muscle, public health services encourage people experiencing possible acute coronary syndrome symptoms or those around them to ...

  7. Cream (pharmacy) - Wikipedia

    en.wikipedia.org/wiki/Cream_(pharmacy)

    Cream. A cream is a preparation usually for application to the skin.Creams for application to mucous membranes such as those of the rectum or vagina are also used. Creams may be considered pharmaceutical products, since even cosmetic creams are manufactured using techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions (dermatoses).

  8. 4-Hydroxycoumarins - Wikipedia

    en.wikipedia.org/wiki/4-Hydroxycoumarins

    So called "super-warfarins" or second-generation anticoagulants in this class, were developed as rodenticides for rodents that have developed warfarin resistance. The second generation agents have even larger lipid-soluble substituents at the 3-position (e.g. brodifacoum ), a chemical change that causes their half-lives in the body to be ...

  9. Prothrombin complex concentrate - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_complex...

    Other uses include a deficiency of one of the included clotting factors, either congenital or due to liver disease, and hemophilia. [18] Several guidelines, including those from the American College of Chest Physicians , recommend prothrombin complex concentrate for warfarin reversal in people with serious bleeding.

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