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Individuals with TEC have a median age of presentation of 18–26 months; however, the disorder may occur in infants younger than 6 months and in children as old as age 10 years. Because of the gradual onset of the anemia, children are often healthier than expected from their low hemoglobin levels. [citation needed]
Erythropoiesis-stimulating agents are only recommended in those with severe anemia. [10] Anemia is the most common blood disorder, affecting about a fifth to a third of the global population. [1] [11] [12] [13] Iron-deficiency anemia is the most common cause of anemia worldwide, and affects nearly one billion people. [14]
Methemoglobinemia mostly affects infants under 6 months of age (particularly those under 4 months) due to low hepatic production of methemoglobin reductase. [ 23 ] [ 24 ] The most at-risk populations are those with water sources high in nitrates , such as wells and other water that is not monitored or treated by a water treatment facility.
During a blood smear, a medical technologist/clinical lab scientist spreads a thin layer of blood on a microscope slide and stains the blood to help differentiate the cells. The technologist/clinical lab scientist then views the blood under a microscope, where the sizes and shapes of the red blood cells can be seen. [2]
In some cases, a drug can cause the immune system to mistakenly think the body's own red blood cells are dangerous, foreign substances. Antibodies then develop against the red blood cells. The antibodies attach to red blood cells and cause them to break down too early. It is known that more than 150 drugs can cause this type of hemolytic anemia ...
This is common in immunocompromised, elderly, and diabetic people. High blood loss can also come from the increased loss of blood during menstruation, childbirth, cancers of the intestines, and disorders that hinder the blood's ability to coagulate. [citation needed] Medications can have adverse effects and cause nutritional anemia as well.
Methotrexate treats cancer, lupus, rheumatoid arthritis, psoriasis but can cause birth defects. Some women can't get it because of abortion laws, fear punishment.
Megaloblastic anemia is a type of macrocytic anemia. An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M ...