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Although the cause for this comorbidity is not yet certain, genetic evidence for a spectrum between cluster A personality disorders/schizophrenia and autism spectrum disorders has been found. [ 81 ] [ 82 ] [ 83 ] [ note 1 ] Tantam suggested that Asperger syndrome may confer an increased risk of developing SPD.
A common presentation of sleep apnea in children with autism is insomnia. [67] All known genetic syndromes which are linked to autism have a high prevalence of sleep apnea. The prevalence of sleep apnea in Down's Syndrome is 50% - 100%. [68] Sleep problems and OSA in this population have been linked to language development. [69]
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
Modern research generally agrees that there is a largely epigenetic etiology of autism spectrum disorders. [2] The terms refrigerator mother and refrigerator parents were coined around 1950 as a label for mothers or fathers of children diagnosed with autism or schizophrenia. Both terms are now regarded as stigmatizing, and no longer used.
In the animal models, the significant effects of VPA in causing ASD-like symptoms was demonstrated mainly in rats exposed to VPA on gestation day 12.5, not in other gestation days like day 9, 14.5, etc. [47] [48] The ASD-like symptoms of mice included decreased distressed pup calls, decreased social exploration, decreased social behaviors ...
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The most striking sign of Timothy syndrome type 1 is the co-occurrence of both syndactyly (about 0.03% of births) and long QT syndrome (1% per year) in a single patient. . Other common symptoms include cardiac arrhythmia (94%), heart malformations (59%), and autism or an autism spectrum disorder (80% who survive long enough for evaluati
Classic autism, also known as childhood autism, autistic disorder, or Kanner's syndrome, is a formerly diagnosed neurodevelopmental disorder first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction and communication as well as restricted, repetitive behaviors, activities, and interests.