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Tonicity. In chemical biology, tonicity is a measure of the effective osmotic pressure gradient; the water potential of two solutions separated by a partially-permeable cell membrane. Tonicity depends on the relative concentration of selective membrane-impermeable solutes across a cell membrane which determine the direction and extent of ...
Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).
Volume contraction. Volume contraction is a decrease in the volume of body fluid, including the dissolved substances that maintain osmotic balance (osmolytes). The loss of the water component of body fluid is specifically termed dehydration. [1]
Hyponatremia. Hyponatremia or hyponatraemia is a low concentration of sodium in the blood. [4] It is generally defined as a sodium concentration of less than 135 mmol/L (135 mEq/L), with severe hyponatremia being below 120 mEq/L. [3][8] Symptoms can be absent, mild or severe. [2][9] Mild symptoms include a decreased ability to think, headaches ...
Solutions used for intravenous rehydration may be isotonic,hypertonic, or hypotonic depending on the cause of dehydration as well as the sodium concentration in the blood. [43] Pure water injected into the veins will cause the breakdown ( lysis ) of red blood cells ( erythrocytes ).
Osmotic concentration. Osmotic concentration, formerly known as osmolarity, [1] is the measure of solute concentration, defined as the number of osmoles (Osm) of solute per litre (L) of solution (osmol/L or Osm/L). The osmolarity of a solution is usually expressed as Osm/L (pronounced "osmolar"), in the same way that the molarity of a solution ...
The science of fluid balance across fluid compartments has practical application in intravenous therapy, where doctors and nurses must predict fluid shifts and decide which IV fluids to give (for example, isotonic versus hypotonic), how much to give, and how fast (volume or mass per minute or hour).
A red blood cell in a hypertonic solution, causing water to move out of the cell. Plasmolysis is the process in which cells lose water in a hypertonic solution. The reverse process, deplasmolysis or cytolysis, can occur if the cell is in a hypotonic solution resulting in a lower external osmotic pressure and a net flow of water into the cell.