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Transitional cell carcinoma is a type of cancer that arises from the transitional epithelium, a tissue lining the inner surface of these hollow organs. [1] It typically occurs in the urothelium of the urinary system ; in that case, it is also called urothelial carcinoma .
Invasive urothelial carcinoma is a type of transitional cell carcinoma. It is a type of cancer that develops in the urinary system: the kidney , urinary bladder , and accessory organs. Transitional cell carcinoma is the most common type of bladder cancer and cancer of the ureter , urethra , renal pelvis , the ureters , the bladder , and parts ...
Primary urethral cancer is rare and contributes to less than 1% of all cancers. It is three times more common in men than women and its incidence rises after the age of 75. [1] Around half of affected people have locally advanced disease when they first present. 54–65% of cases are of the urothelial carcinoma type. [1]
Urachal cancer is a very rare type of cancer arising from the urachus or its remnants. [1] The disease might arise from metaplastic glandular epithelium or embryonic epithelial remnants originating from the cloaca region. [2] It occurs in roughly about one person per 1 million people per year varying on the geographical region. [3]
M8120/1 Urothelial papilloma, NOS Papilloma of bladder (C67._) Transitional cell papilloma, NOS; M8120/2 Transitional cell carcinoma in situ Urothelial carcinoma in situ; M8120/3 Transitional cell carcinoma, NOS Urothelial carcinoma, NOS; Transitional carcinoma; M8121/0 Schneiderian papilloma, NOS (C30.0, C31._) Sinonasal papilloma, NOS
Should the transitional cell carcinoma grow toward the inner surface of the bladder via finger-like projections, it is known as papillary carcinoma. Otherwise, it is known as flat carcinoma. [ 11 ] Either form can transition from non-invasive to invasive by spreading into the muscle layers of the bladder.
The Paris System for reporting urine cytology, version 2.0, ranging from negative to positive for high grade urothelial carcinoma. [1] Urine cytology is a test that looks for abnormal cells in urine under a microscope. The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions.
Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [59] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [59]
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