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A few well-controlled studies have been carried out investigating the safety and efficacy of sucralfate in children and pregnant women (Pregnancy Category B). [ 1 ] [ 27 ] [ 28 ] Mechanism of action
There is no clear first-line tocolytic agent. [6] [7] Current evidence suggests that first line treatment with β 2 agonists, calcium channel blockers, or NSAIDs to prolong pregnancy for up to 48 hours is the best course of action to allow time for glucocorticoid administration.
The duration of estradiol esters in oil solution by intramuscular injection is dose-dependent. [282] With estradiol valerate, it is reported that a dose of 5 mg has a duration of 7 to 8 days, [274] 10 mg a duration of 10 to 14 days, [265] [282] 40 mg a duration of 2 to 3 weeks, and 100 mg a duration of 3 to 4 weeks. [282]
Gastritis is the inflammation of the lining of the stomach. [1] It may occur as a short episode or may be of a long duration. [1] There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). [1]
English: Skeletal formula of sucralfate—a cytoprotective medication used in the treatment of GERD, gastritis, peptic ulcer disease, stress ulcers and dyspepsia. Date 22 September 2023
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Gestational age: 3 weeks and 0 days until 3 weeks and 6 days old. 22–28 days from last menstruation. Embryonic age: Week nr 2. 1 week old. 8–14 days from fertilization.
In Ireland, under the Health (Regulation of Termination of Pregnancy) Act 2018, fetal viability is defined as "the point in a pregnancy at which, in the reasonable opinion of a medical practitioner, the foetus is capable of survival outside the uterus without extraordinary life-sustaining measures" [Definitions (Part 2)(8)]. [10]
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