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The cell nucleus (from Latin nucleus or nuculeus 'kernel, seed'; pl.: nuclei) is a membrane-bound organelle found in eukaryotic cells.Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many.
Nuclear DNA is a nucleic acid, a polymeric biomolecule or biopolymer, found in the nucleus of eukaryotic cells.Its structure is a double helix, with two strands wound around each other, a structure first described by Francis Crick and James D. Watson (1953) using data collected by Rosalind Franklin.
In biology, the nuclear matrix is the network of fibres found throughout the inside of a cell nucleus after a specific method of chemical extraction. According to some it is somewhat analogous to the cell cytoskeleton. In contrast to the cytoskeleton, however, the nuclear matrix has been proposed to be a dynamic structure.
Nuclear organization refers to the spatial organization and dynamics of chromatin within a cell nucleus during interphase. There are many different levels and scales of nuclear organisation. At the smallest scale, DNA is packaged into units called nucleosomes, which compacts DNA about 7-fold.
Nucleoplasm is quite similar to the cytoplasm, with the main difference being that nucleoplasm is found inside the nucleus while the cytoplasm is located inside the cell, outside of the nucleus. Their ionic compositions are nearly identical due to the ion pumps and permeability of the nuclear envelope, however, the proteins in these two fluids ...
Genomic DNA is tightly and orderly packed in the process called DNA condensation, to fit the small available volumes of the cell. In eukaryotes, DNA is located in the cell nucleus, with small amounts in mitochondria and chloroplasts. In prokaryotes, the DNA is held within an irregularly shaped body in the cytoplasm called the nucleoid. [97]
Nuclear pores are found in the nuclear envelope that surrounds the cell nucleus in eukaryotic cells. The nuclear envelope is studded by a great number of nuclear pores that give access to various molecules, to and from the nucleoplasm and the cytoplasm. Small molecules can diffuse easily but other larger molecules need to be transported across. [1]
The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of eukaryote cells. It is composed of intermediate filaments and membrane associated proteins . Besides providing mechanical support, the nuclear lamina regulates important cellular events such as DNA replication and cell division .