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Mannose (D-mannose) is used as a dietary supplement to prevent recurrent urinary tract infections (UTIs). [ 9 ] [ 10 ] As of 2022 [update] , one review found that taking mannose was as effective as antibiotics to prevent UTIs, [ 9 ] while another review found that clinical trial quality was too low to allow any conclusion about using D ...
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Treatment is usually effective with antibiotics once the result of the urine culture identifies the precise bacteria involved in the infection. D-mannose (which is also anti-inflammatory) is also used by some pet owners as a natural alternative to antibiotic treatment although this may be less targeted and specific than prescribed antibiotics ...
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
Urinary tract infections, even asymptomatic presence of bacteria in the urine, are more concerning in pregnancy due to the increased risk of kidney infections. [42] During pregnancy, high progesterone levels elevate the risk of decreased muscle tone of the ureters and bladder, which leads to a greater likelihood of reflux, where urine flows ...
One way the most-recently discovered lectin pathway is activated is through mannose-binding lectin protein. MBL binds to carbohydrates (to be specific, D-mannose and L-fucose residues) found on the surfaces of many pathogens. For example, MBL has been shown to bind to: yeasts such as Candida albicans [19] [20] viruses such as HIV [21] and ...
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